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Figure 2 | BMC Surgery

Figure 2

From: A therapeutic exploratory study to determine the efficacy and safety of calcineurin-inhibitor-free de-novo immunosuppression after liver transplantation: CILT

Figure 2

Flow chart of the CILT study. Derived from an optimal two-stage design for a phase II clinical trial with the following parameters: p 0 = 0.8, p 1 = 0.95, error probability α = 0.05, and error probability β = 0.2. Abbr.: n, number of patients; r, maximum number of responders at which H 0 will not be rejected; H 1, alternative hypothesis.

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BMC Surgery

ISSN: 1471-2482

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