Table 1 Comparisons between TURP-diagnosed PC patients with RP and nRP
Variables | RP (n = 1,313) | nRP (n = 3,364) | P value | ||
|---|---|---|---|---|---|
N | % | N | % | ||
Age (ys.) | < 0.001 | ||||
Median | 70.00 | 75.00 | |||
IQR (range) | 63.00–77.00 (41–90) | 65.00–83.00 (24–90) | |||
Race | < 0.001 | ||||
White | 1,173 | 89.3 | 2,434 | 72.4 | |
Black | 71 | 5.4 | 578 | 17.2 | |
Others | 67 | 5.1 | 341 | 10.1 | |
Missing | 2 | 0.2 | 11 | 0.3 | |
Marital status | < 0.001 | ||||
Married | 901 | 68.6 | 1,739 | 51.7 | |
Single | 331 | 25.2 | 1,414 | 42.0 | |
Missing | 81 | 6.2 | 211 | 6.3 | |
Annual income | 0.07 | ||||
< 7, 000$ | 659 | 50.2 | 1,591 | 47.3 | |
≥ 7,000$ | 654 | 49.8 | 1,772 | 52.7 | |
Missing | 1 | 0.0 | |||
Home location | < 0.001 | ||||
Big city | 585 | 44.6 | 1,829 | 54.4 | |
Small city | 728 | 55.4 | 1,534 | 45.6 | |
Missing | 1 | 0.0 | |||
Diagnosis year | < 0.001 | ||||
2010–2014 | 595 | 45.3 | 1,319 | 39.2 | |
2014–2019 | 718 | 54.7 | 2,045 | 60.8 | |
PSA | < 0.001 | ||||
0.1 or less nanograms/milliliter (ng/ml) | 11 | 0.8 | 6 | 0.2 | |
Test ordered, results not in the chart | 29 | 2.2 | 84 | 2.5 | |
98.0 ng/ml or greater | 6 | 0.5 | 2,704 | 80.4 | |
Missing | 1,267 | 96.5 | 570 | 16.9 | |
Pathological Gleason score | / | ||||
≤ 6 | 865 | 65.9 | / | / | |
7 | 391 | 29.8 | / | ||
8–10 | 57 | 4.3 | / | / | |
Stage | < 0.001 | ||||
Localized | 1,187 | 90.4 | 163 | 4.8 | |
Reginal | 111 | 8.5 | 126 | 3.7 | |
Distant | 7 | 0.5 | 2,900 | 86.2 | |
Missing | 8 | 0.6 | 175 | 5.2 | |
Month to treatment (mo.) | < 0.001 | ||||
N | 1,311 | 99.8 | 2,752 | 81.8% | |
Median | 0.00 | 0.00 | |||
IQR (range) | 0.00–0.00 (0.00–12.00) | 0.00–1.00 (0.00–23.00) | |||
Missing | 2 | 0.2 | 612 | 18.2% | |
CDS | < 0.001 | ||||
Yes | 1,313 | 100 | 100 | 3.0 | |
No | 0 | 0 | 3,186 | 94.7 | |
Missing | 78 | 2.3 | |||
Lymph node dissection | < 0.001 | ||||
1 to 3 regional lymph nodes removed | 65 | 5.0 | 14 | 0.4 | |
4 or more regional lymph nodes removed | 1,006 | 76.6 | 5 | 0.1 | |
Biopsy only | 0 | 0 | 127 | 3.8 | |
Missing | 242 | 18.4 | 3,218 | 95.7 | |
Radiation therapy | 0.72 | ||||
Beam | 8 | 0.6 | 728 | 21.6 | |
Others | 12 | 0.4 | |||
No/known | 1305 | 99.4 | 2,624 | 78.0 | |
Chemotherapy | < 0.001 | ||||
Yes | 17 | 1.3 | 435 | 12.9 | |
No/unknown | 1,296 | 98.7 | 2,929 | 87.1 | |
Systemic therapy | < 0.001 | ||||
In and before surgery | 4 | 0.3 | 52 | 1.5 | |
After surgery | 24 | 1.8 | 306 | 9.1 | |
No/ unknown | 1,285 | 97.9 | 3,006 | 89.4 | |
CSM | < 0.001 | ||||
Death | 60 | 4.6 | 1,674 | 49.8 | |
Alive or other death | 1,253 | 95.4 | 1,690 | 50.2 | |
OM | < 0.001 | ||||
Death | 493 | 37.5 | 2,154 | 64.0 | |
Alive | 820 | 62.5 | 1,210 | 36.0 | |
Survival time (mo.) | < 0.001 | ||||
Median | 30.00 | 16.00 | |||
IQR (range) | 12.00–58.00 (1-119) | 7.00–33.00 (1-118) | |||