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Table 1 Baseline data of all patients and patients with or without radiographic (CT) sarcopenia

From: Associations of body composition parameters with postoperative outcome and perineural tumour invasion after oncological pancreatic resection

  

Total Patients (n = 437)

Sarcopenia (n = 240)

No sarcopenia (n = 197)

p value

Preoperative Status

    
 

Age (years) (median, LQ; UQ)

69 (61;74)

70 (63;75)

67 (60;73)

0.014#

 

Female (n, %)

201 (46%)

84 (35%)

117 (59.4%)

< 0.001*

 

ASA Status (median, LQ; UQ)

2 (2;3)

2 (2;3)

2 (2;3)

0.147#

 

BMI (kg/m2) (median, LQ; UQ)

24.2(22.2;26.7)

23.5 (21.2;25.4)

25.4(23.1;28.1)

< 0.001#

 

GLIM Malnutrition (n, %)

79 (18.1%)

61 (25.4%)

18 (9.1%)

< 0.001*

 

Obesity (n, %)

36 (8.2%)

12 (5%)

24 (12.2%)

0.008*

 

Diabetes (n, %)

122 (27.9%)

66 (27.5%)

56 (28.4%)

0.831*

 

CT SMI (cm2/m2)

(median, LQ; UQ)

44.5 (38.7;50.7)

41.9 (36.8;47.5)

47.1(41.3;55.8)

< 0.001#

 

CT VATI (cm2/m2)

(median, LQ; UQ)

39.1(21.2;62.1)

38.9(19.8;59.2)

40.5(22.6;65.1)

0.502#

 

CT VAT (cm2)

(median, LQ; UQ)

113.2 (62.5;182.4)

113.8 (62.1;183.4)

113.2 (62.6;178.8)

0.888#

 

Visceral obesity (n, %)

201 (46%)

104 (43.3%)

97 (49.2%)

0.247*

 

Neoadjuvant treatment

 
 

  Chemotherapy (n, %)

79 (18.1%)

41 (17.1%)

38 (19.3%)

0.618*

 

  Radiotherapy (n, %)

4 (0.9%)

1 (0.4%)

3 (1.5%)

0.332*

 

  Combination (n, %)

1 (0.2%)

0

1 (0.5%)

0.451*

 

Preoperative biliary stenting (n, %)

145 (33.2%)

98 (40.8%)

47 (23.9%)

< 0.001*

Operation

 
 

  Pancreaticoduodenectomy (n, %)

268 (61.3%)

161 (67.1%)

107 (54.3%)

0.008*

 

  Distal Pancreatectomy (n, %)

104 (23.8%)

45 (18.8%)

59 (29.9%)

0.007*

 

  Total Pancreatectomy (n, %)

65 (14.9%)

34 (14.2%)

31 (15.7%)

0.686*

 

Duration of Operation (min)

(median, LQ; UQ)

379

(302;451.5)

383

(317.8;455.5)

373

(284.5;450)

0.173#

Histopathological data

    
 

  PDAC (n, %)

422 (96.6%)

235 (97.9%)

187 (94.9%)

0.114*

 

  Other (n, %)

15 (3.4%)

5 (2.1%)

10 (5.1%)

 

AJCC stage (8th edition)

   

0.975*

 

  0 (n, %)

3 (0.7%)

1 (0.4%)

2 (1.0%)

 

  IA (n, %)

32 (7.3%)

18 (7.5%)

14 (7.1%)

 

  IB (n, %)

62 (14.2%)

36 (15%)

26 (13.2%)

 

  IIA (n, %)

22 (5%)

12 (5%)

10 (5.1%)

 

  IIB (n, %)

140 (32%)

79 (32.9%)

61 (31%)

 

  III (n, %)

144 (33%)

76 (31.7%)

68 (34.5%)

 

  IV (n, %)

34 (7.8%)

18 (7.5%)

16 (8.1%)

 

Perineural tumour invasion

   

0.118*

 

  Pn0 (n, %)

87 (19.9%)

41 (17.1%)

46 (23.4%)

 

  Pn1 (n, %)

350 (80.1%)

199 (82.9%)

151 (76.6%)

  1. Symbols: # Man-Whitney-U test; *Fisher’s exact test
  2. Abbreviations ASA = American Society of Anesthesiologists; BMI = Body mass index; GLIM = Global leadership initiative on malnutrition; CT = Computed tomography; SMI = Skeletal muscle index, VAT = Visceral adipose tissue; VATI = Visceral adipose tissue index; PDAC = Pancreatic ductal adenocarcinoma; AJCC = American Joint Committee on Cancer