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Table 1 Clinical characteristics of 186 children with NB

From: Risk factors, impact and treatment of postoperative lymphatic leakage in children with abdominal neuroblastoma operated on by laparotomy

Characteristics

lymphatic leakage1,2

Non-lymphatic leakage

Results3

p Value

(n = 32)

(n = 154)

Gender

Male

16 (50)

76 (49.4)

0.004

0.974

 

Female

16 (50)

78 (50.6)

  

Age (months)

 

35 (22, 46)

42 (23, 70)

1.626

0.106

INRG stage

L1

2 (6.3)

51 (33.1)

9.43

0.024

 

L2

7 (21.8)

25 (16.2)

  
 

M

21 (65.6)

72 (46.8)

  
 

MS

2 (6.3)

6 (3.9)

  

INRG risk

Very low

2 (6.3)

55 (35.7)

12.545

0.006

 

Low

2 (6.3)

15 (9.7)

  
 

Intermediate

5 (15.6)

12 (7.8)

  
 

High

22 (68.7)

71 (46.1)

  
 

Unknown

1 (3.1)

1 (0.7)

  

Pathology

NB&GNBn

32 (100)

124 (80.5)

7.433

0.006

 

GNBi&GN

0

30 (19.5)

  

Preoperative chemotherapy

Yes

30 (93.7)

94 (61)

12.757

< 0.001

 

No

2 (6.3)

60 (39)

  

IDRFs

Yes

28 (87.5)

89 (57.8)

12.021

0.002

 

No

4 (12.5)

65 (42.2)

  

Tumor crosses the midline at surgery

Yes

23 (71.9)

47 (30.5)

19.306

< 0.001

 

No

9 (28.1)

107 (69.5)

  

Maximum diameter of tumor at surgery (cm)

 

6.7 (5, 8.1)

5.9 (3.7, 8.2)

-1.334

0.184

Number of invaded blood vessels

 

4 (2, 6)

0 (0, 3)

4.977

< 0.001

Number of resected lymphatic regions

 

5 (4, 9)

3 (2, 4)

5.996

< 0.001

Middle-upper region resected

Yes

22 (68.8)

115 (74.7)

22.669

< 0.001

 

No

10 (31.2)

39 (25.3)

  

Degree of surgical resection

Gross total resection

32 (100)

154 (100)

  
 

< 90% resection

0

0

  

Blood loss (ml)

 

30 (18.5, 50)

10 (5, 20)

4.345

< 0.0001

Operation time (h)

 

6.4 (4.9, 7.5)

3.5 (3, 5)

-5.777

< 0.0001

  1. INRG, International Neuroblastoma Risk Group; IDRFs, Image-defined risk factors; NB, neuroblastoma; GNBn, ganglioneuroblastoma, nodular; GNBi, ganglioneuroblastoma, intermixed; GN, ganglioneuroma.
  2. 1Continuous variables are presented as the median and interquartile range.
  3. 2Classification variables are presented as numbers (percent).
  4. 3Results represent the z value of the Mann-Whitney test and the χ2 value of the chi-square test, respectively.