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Table 1 Preoperative clinical characteristics of patients, comparison of laparoscopic cholecystectomy and conversion to open cholecystectomy groups

From: Minimally invasive approach in a rare emergency surgery, gallbladder perforation

 

Total (n = 42)

LC group

COC group

p = value

(n = 28, 66.6%)

(n = 14, 33.3%)

Age, median (range), year

68 (55–85)

71.50 (55–85)

68 (59–83)

0.218*

Sex, F:M, n

16:26

14:14

2:12

0.025**

History of calculi before perforation, n (%)

18 (42.9%)

13 (46.4%)

5 (35.7%)

0.508**

Modes of diagnosis, n (%)

   

0.161**

 US

16 (38.1%)

12 (42.9%)

4 (28.6%)

 CT

22 (52.4%)

15 (53.6%)

7 (50.0%)

 MRI

4 (9.5%)

1 (3.6%)

3 (21.4%)

Wall thickness, median, milimeter

14 (7–16)

14 (8–16)

13 (7–14)

0.681*

Presenting complaint, n (%)

    

 Abdominal pain

34 (80.95%)

24 (85.7%)

10 (71.4%)

0.266**

 Vomiting

18 (42,85%)

11 (39.3%)

7 (50.0%)

0.508**

 Fever

16 (38.09%)

12 (42.9%)

4 (28.6%)

0.369**

Comorbidities, n (%)

    

 Diabetus Mellitus

18 (42.9%)

10 (35.71%)

8 (57.14%)

0.186**

 Hypertension

26 (61.9%)

17 (60.71%)

9 (64.28%)

0.822**

 Coronary artery disease

22 (52.4%)

16 (57.14%)

6 (42.85%)

0.382**

 Cerebrovascular disease

8 (19.0%)

5 (17.85%)

3 (21.42%)

0.781**

 Chronic lung disease

8 (19.0%)

5 (17.85%)

3 (21.42%)

0.781**

ASA, n (%)

   

0.392**

 I

1 (2.4%)

1 (3.6%)

0

 II

6 (14.3%)

3 (10.7%)

3 (21.4%)

 III

24 57.1%)

18 (64.3%)

6 (42.9%)

 IV

11 (26.2%)

6 (21.4%)

5 (35.7%)

CCI, median (IQR)

2 (1–6)

2 (1–3)

3 (1–6)

0.02*

Tokyo classification, n (%)

   

0.007**

 I

7 (16.7%)

6 (21.4%)

1 (7.1%)

 II

19 (45.2%)

16 (57.1%)

3 (21.4%)

 III

16 (38.1%)

6 (21.4%)

10 (71.4%)

Preoperative WBC, median (range)

12300 (8600–28920)

11900 (9800–24210)

12300 (8600–28920)

0.486*

Preoperative glucose, median (range)

146 (111–206)

153.50 (111–206)

146.0 (135–176)

0.789*

  1. n: number, SD: standard deviation, F: female, M: male, US: Ultrasonography, CT: Computed tomografi, MRI: magnetic resonance imaging, WBC: white blood cell, MODS: Multiple Organ Dysfunction Sydrome, LC: laparoscopic cholecystectomy, COC: conversion to open cholecystectomy, CCI: Charlson comorbidity index, IQR: Interquartile range, ASA: American Society of Anaesthetiologist,: Clavien – Dindo ≥ III
  2. Bold values indicate statistically significant p values (p < 0.05)
  3. *: Mann -Whitney U test, **: Chi-square test, ***: Fisher’s exact tests