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Table 1 Cont (4)

From: Primary schwannoma of the thyroid gland: analysis of case characteristics and review of the literature

Reference

Sex/

Age

Size(cm)/Location

Presentation

thyroid function

Preoperative

FNAC Result

Indication of surgery or Preoperative diagnosis

Surgery

Intraopera-

tive frozen section

Histological examination

IHC

Gustafson L M, et al.,

2001 [31]

F/20

2.5/Right

No symptoms

Normal

inflammatory cells with hemosiderin

-

Right hemithyroidectomy

-

Antoni A and Antoni B

S-100 protein(+)

Al-Ghamdi S, et al.,

2000 [17]

F/42

14.0/Right

Breathing difficulties;Hoarse voice

Normal

non-diagnostic (acellular)

Suspicious malignancy

Total thyroidectomy

-

Not classified

S-100 protein(+)

Jayaram G.,

1999 [46]

M/41

4.0/Right

No symptoms

Normal

Spindle shaped cells

Thyroid schwannoma

Nodule Removal

-

Antoni A

S-100 protein(+)

Sugita R, et al.,

1998 [18]

M/22

1.0/Right

Facial flushing

and Easy fatigue

Normal

Inflammatory tissue

-

Right hemithyroidectomy

-

Antoni A and Antoni B

-

Mikosch P, et al.,

1997 [15]

M/31

3.9/Right

A feeling of discomfort in the throat

-

Long spindle cells

Benign tumor (Schwannoma or neurofibromatosis)

Nodule Removal

-

Antoni A

-

Aoki T, et al.,

1993 [12]

M/57

3.6/Right

No symptoms

Normal

-

Suspicious malignancy

Nodule Removal

Consider benign tumor

Antoni A

S-100 protein(+)

Andrion A, et al.,

1988 [54]

F/33

5.0/Right

No symptoms

Normal

-

Benign tumor

Nodule Removal

Spindle cell tumors

Antoni A and Antoni B

S-100 protein(+)

DELANEY W E, et al.,

1964 [5]

F/50

2.5/Right

No symptoms

Normal

-

-

Right hemithyroidectomy

Consider benign tumor

Antoni B

-

  1. FNAC: Fine needle aspiration cytology;IHC: Immunohistochemistry; FGFR1: Fibroblast growth factor receptor 1; - : Not stated