Table 3 Clinical risk factors for 40-day postoperative IAL
Variables | Univariable Cox analysis | Multivariable Cox analysis | ||
|---|---|---|---|---|
HR (95%CI) | P | HR (95%CI) | P | |
Age(year) | 0.98 (0.95–1.02) | 0.399 | ||
Tumor size(cm) | 1.00 (0.98–1.01) | 0.725 | ||
Surgery time(min) | 1.00 (1.00–1.00) | 0.777 | ||
Sex | ||||
Female | 1.00 (Reference) | |||
Male | 0.77 (0.40–1.46) | 0.417 | ||
BMI(kg/m2) | ||||
<18.5 | 1.00 (Reference) | 1.00 (Reference) | ||
18.5–23.9 | 0.60 (0.22–1.62) | 0.313 | 0.62 (0.22–1.69) | 0.347 |
≥ 24 | 2.69 (1.10–6.60) | 0.030 | 2.54 (1.01–6.38) | 0.048 |
Pathology type | ||||
Squamous cell carcinoma | 1.00 (Reference) | 1.00 (Reference) | ||
Adenocarcinoma | 0.12 (0.02–0.90) | 0.039 | 0.20 (0.09–1.02) | 0.054 |
Other types | 1.78 (0.78–4.09) | 0.174 | 1.19 (0.50–2.85) | 0.695 |
Diabetes | ||||
No | 1.00 (Reference) | |||
Yes | 0.48 (0.12–1.99) | 0.312 | ||
Cardiovascular disease | ||||
No | 1.00 (Reference) | |||
Yes | 0.28 (0.07–1.17) | 0.081 | ||
Tumor location | ||||
Upper thoracic esophagus | 1.00 (Reference) | |||
Middle thoracic esophagus | 1.22 (0.46–3.23) | 0.686 | ||
Lower thoracic esophagus | 0.44 (0.15–1.31) | 0.140 | ||
Infection | ||||
No | 1.00 (Reference) | 1.00 (Reference) | ||
Yes | 3.02 (1.57–5.82) | < 0.001 | 2.39 (1.22–4.70) | 0.011 |
TNM stage | ||||
I/II | 1.00 (Reference) | |||
III | 0.79 (0.33–1.87) | 0.587 | ||
IV | 1.15 (0.56–2.37) | 0.707 | ||
Surgical method | ||||
Minimally invasive surgery | 1.00 (Reference) | |||
Open surgery | 1.05 (0.52–2.11) | 0.902 | ||