Table 1 Differences between wide local excision (WLE) and micrographically oriented histographic surgery (Mohs)

Indications

SCC and BCC in low-risk sites (lower limbs)

Early melanomas

Tumors at high-risk sites (eye, ear)

Recurrent tumors

Tumors at irradiated skin or chronic wounds

Aggressive tumors

Invasive tumors

Tumors > 2 cm

Immunosuppressed patients

[2, 3]

Incision mode

Bread loaf excision (elliptical incision that involves the tumor and surrounding tissue, involves < 1–2% of the specimen margin)

Start by resecting the tumor and then gradual removal of surrounding tissue to involve a full range of tumor extension

[1, 17]

Microscopic analysis

By the pathologist

By Mohs surgeon

Melanoma recurrence risk

7%

< 1%

[22]