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Table 3 Perioperative outcomes and pathological results

From: Comparison of low-pressure and standard-pressure pneumoperitoneum laparoscopic cholecystectomy in patients with cardiopulmonary comorbidities: a double blinded randomized clinical trial

Variable

LPLC group (n = 62)

SPLC group (n = 62)

Difference (95% CI)

P§

Duration of analgesic (min) *

73.0(36 ~ 210)

77.7(30 ~ 175)

-4 (-10.00 ~ 6.000)

0.647#

Intra-abdominal operative time (min) *

49.3(10 ~ 187)

46.5(15 ~ 127)

3.5 (-7.000 ~ 10.00)

0.739#

EBL (ml) †

   

0.207

<5

34(54.8)

34(54.8)

-

 

5–20

23(37.1)

17(27.4)

-

 

>20

5(8.1)

11(17.7)

-

 

Blood transfusion

0(0)

0(0)

-

-

Intraoperative bile spillage

10(16.1)

7(11.3)

4.8 (-8.8 ~ 18.4)

0.433

Bile duct injury

0(0)

0(0)

-

-

Drainage placement

18(29.0)

14(22.6)

6.5 (-10 ~ 22.5)

0.412

Postoperative complication

    

Bile leak

0(0)

0(0)

-

-

Intraabdominal hemorrhage

0(0)

0(0)

-

-

Delayed wound healing

0(0)

0(0)

-

-

Subcutaneous emphysema

0(0)

0(0)

-

-

Cardiopulmonary events ‡

0(0)

0(0)

-

-

Clavien-Dindo grade I-V

0(0)

0(0)

-

-

Highest temperature on postoperative day one *

36.8(36.2 ~ 39.4)

36.7(36.0 ~ 39.0)

0 (0.000 ~ 0.2000)

0.211#

Time to fist flatus, hours *

22.5(9 ~ 47.5)

21.9(4 ~ 46.5)

0.75 (-2.000 ~ 2.000)

0.853#

Duration of postoperative hospital stay, days *

3.0(1 ~ 8)

3.0(1 ~ 8)

-

0.378#

Mortality within 30 days

0(0)

0(0)

-

-

VAS

    

Preoperative VAS *

0(0 ~ 8)

0(0 ~ 8)

0 (0 ~ 0)

0.209#

Mean postoperative VAS *

1.77(0.8 ~ 6)

1.74(0.2 ~ 4.3)

0.105 (-0.160 ~ 0.500)

0.203#

Mean VAS post-VAS pre *

1.0(-4.7~ 4.8)

0.8(-5.0 ~ 4.0)

0.17 (-0.875 ~ 0.500)

0.710#

Main postoperative pathology

    

Gallstones only

51(82.3)

48(77.4)

-

 

Gallbladder polyps with or without gallstones

7(11.3)

13(21.0)

-

 

Cholecystitis only

4(6.5)

1(1.6)

-

 
  1. Values in parentheses are percentages unless indicated otherwise; *values are median (range). LC, laparoscopic cholecystectomy. EBL, estimated blood loss. VAS, visual analog score. †Considering the minimal blood loss during most LC procedures, EBL was categorized as grade 1 (< 5 ml), grade 2 (≥ 5 ml and ≤ 20 ml), and grade 3 (> 20 ml). ‡ include but not limited to angina pectoris, myocardial infarction, arrhythmia, heart failure, hypoxemia, atelectasis, pulmonary infection, pulmonary embolism, et al. § χ2 test, except # Mann–Whitney U test