Table 1 Preoperative characteristics of HCC patients with recurrence after hepatectomy according to recurrence period
|  | Early recurrence (n = 38) | Late recurrence (n = 113) | p value |
|---|---|---|---|
Age | 71 (38–84) | 69 (38–86) | 0.74 |
Gender (Male / Female) | 30/8 | 96/17 | 0.39 |
BMI | 22.7 (13.2–34.5) | 22.9 (15.6–31.4) | 0.87 |
Albumin (g/dL) | 3.7 (2.3–4.6) | 3.9 (2.3–5.0) | 0.15 |
Total bilirubin (mg/dL) | 0.7 (0.3–1.5) | 0.7 (0.2–2.5) | 0.39 |
PT-INR | 1.06 (0.89–1.30) | 1.05 (0.88–1.41) | 0.55 |
Platelet count (× 104/μL) | 19.2 (6.2–179.0) | 17.5 (4.3–259.7) | 0.13 |
AFP (ng/mL) | 76 (2–605,100) | 11 (1–242,000) | 0.002 |
DCP (mAU/mL) | 795 (15–174,400) | 92 (10–51568) | 0.004 |
ICG R15 (%) | 12.7 (3.7–68.6) | 13.2 (1.6–49.9) | 0.93 |
LHL15 | 0.934 (0.831–0.965) | 0.930 (0.679–0.984) | 0.96 |
PNI | 45.1 (26.6–55.9) | 45.9 (26.0–59.7) | 0.40 |
Underlying liver disease NBNC / HBV / HCV | 20 (53%) / 4 (11%) / 14 (37%) | 37 (33%) / 15 (13%) / 61 (54%) | 0.089 |
Maximum tumor diameter (cm) | 6.0 (1.8–20.0) | 3.5 (0.5–26.0) |  < 0.001 |
Single / Multiple tumor nodules | 21 (55%) / 17 (45%) | 91 (81%) / 22 (20%) | 0.002 |
BCLC stage 0/A/B/C | 1 (3%)/ 18 (47%)/ 11 (29%)/ 8 (21%) | 14 (12%)/ 86 (76%)/ 12 (11%)/ 1 (1%) |  < 0.001 |
Up-to-7 criteria in / out | 18 (47%) / 20 (53%) | 84 (74%) / 29 (26%) | 0.002 |
5–5-500 criteria in / out | 14 (37%) / 24 (63%) | 72 (64%) / 41 (36%) | 0.004 |