Table 4 Uni- and multivariate analysis of preoperative risk factors for recurrence among all HCC cases who survived more than 6 months after initial hepatectomy

Age

1.02 (1.00–1.04)

0.078

Gender (Male / Female)

0.82 (0.52–1.30)

0.40

BMI

0.97 (0.92–1.02)

0.21

Albumin (g/dL)

0.70 (0.48–1.02)

0.06

Total bilirubin (mg/dL)

1.15 (0.66–2.01)

0.64

PT-INR

6.18 (1.23–31.10)

0.027

Platelet count (× 10⁴/μL)

1.00 (0.99–1.01)

0.46

AFP (ng/mL)

1.00 (1.00–1.00)

0.63

DCP (mAU/mL)

1.00 (1.00–1.00)

0.44

ICG R15 (%)

1.04 (1.00–1.03)

0.061

LHL15

0.019 (0.00–0.75)

0.034

0.019 (0.00–0.75)

0.034

PNI

0.96 (0.93–0.99)

0.013

Underlying liver disease

NBNC / HBV / HCV

0.69 (0.47–1.00)

0.05*

Maximum tumor diameter (cm)

1.03 (0.98–1.08)

0.25

Multiple tumor nodules

1.41 (0.93–2.15)

0.11

BCLC stage 0/A/B/C

2.37 (1.16–4.82)

0.018**

Up-to-7 criteria out

1.29 (0.88–1.89)

0.20

5–5-500 criteria out

1.01 (0.71–1.44)

0.97

Anatomical resection

0.84 (0.59–1.21)

0.35

Laparoscopic

1.23 (0.80–1.89)

0.35