Skip to main content

Table 2 Perioperative variables and outcomes of patients with early-, middle- or late-onset pancreatic adenocarcinoma stratified regarding type of resection (PD vs. DP)

From: Perioperative outcomes in an age-adapted analysis of the German StuDoQ|Pancreas registry for PDAC

Type of surgery

PD

(n = 2.412)

DP

(n = 599)

Pancreaticoduodenectomy

Distal Pancreatectomy

P value

Onset

n

  

EOPC

83

MOPC

1123

LOPC

1.206

EOPC

27

MOPC

276

LOPC

296

 

Median duration (min)

330

[272—403]

212

[163—269]

352

[290—441]

342

[278—415]

320

[265—384]

240

[165—315]

218.5

[172—277]

203

[155—253]

PPD < 0.01

PDP< 0.01

Median stay hospital (days)

16

[12–23]

14.5

[11–22]

15

[12–22]

15

[12–21]

17

[13–24]

12

[11–18]

14

[11–21]

15

[12–23]

PPD < 0.01

PDP< 0.05

Median stay ICU (days)

3

[1–5]

1

[1–3]

2

[1–4]

2

[1–4]

3

[1–5]

1

[0 – 2]

1

[1–3]

2

[1–4]

PPD < 0.01

PDP = 0.07

Resection status

        

PPD = 0.87

PDP = 0.69

 R0

1832

(76.0%)

448

(74.8%)

62

(74.4%)

855

(76.1%)

915

(75.9%)

22

(81.5%)

206

(74.6%)

220

(74.3%)

 

 R1

526

(21.8%)

132

(22.0%)

20

(24.1%)

246

(21.9%)

260

(21.6%)

5

(18.5%)

60

(21.7%)

67

(22.6%)

 

 R2

26

(1.1%)

5

(0.8%)

1

(1.2%)

11

(1.0%)

14

(1.2%)

-

2

(0.7%)

3

(1.0%)

 

 Unknown

28

(1.2%)

14

(2.3%)

-

11

(1.0%)

17

(1.4%)

-

8

(2.9%)

6

(2.0%)

 

CR-POPF

        

PPD = 0.82

PDP = 0.20

 No

2221

(92.1%)

458

(76.5%)

78

(94.0%)

1033

(92.0%)

1110

(92.0%)

24

(88.9%)

205

(74.3%)

229

(77.4%)

 

 Yes

191

(7.9%)

141

(23.5%)

5

(6.0%)

90

(8.0%)

96

(8.0%)

3

(11.1%)

71

(25.7%)

67

(22.6%)

 

CR-PPH

        

PPD = 0.82

PDP = 0.97

 No

2203

(91.3%)

578

(96.5%)

77

(92.8%)

1022

(91.0%)

1104

(91.5%)

26

(96.3%)

266

(96.4%)

286

(96.6%)

 

 Yes

209

(8.7%)

21

(3.5%)

6

(7.2%)

101

(9.0%)

102

(8.5%)

1

(3.7%)

10

(3.6%)

10

(3.4%)

 

CR-DGE

        

PPD = 0.14

PDP = 0.06

 No

2172

(90.0%)

572

(95.5%)

80

(96.4%)

1011

(90.0%)

1081

(89.6%)

27

(100%)

268

(97.1%)

277

(93.6%)

 

 Yes

240

(10.0%)

27

(4.5%)

3

(3.6%)

112

(10.0%)

125

(10.4%)

-

8

(2.9%)

19

(6.4%)

 

Complication

        

PPD < 0.01

PDP = 0.18

 None/Minor (Clavien-Dindo < 3a)

1734

(71.9%)

459

(76.6%)

69

(83.1%)

829

(73.8%)

836

(69.3%)

24

(88.9%)

215

(77.9%)

220

(74.3%)

 

 Major (Clavien-Dindo ≥ 3a)

678

(28.1%)

140

(23.4%)

14

(16.9%)

294

(26.2%)

370

(30.7%)

3

(6.3%)

61

(22.1%)

76

(25.7%)

 

Mortality

        

PPD < 0.01

PDP = 0.13

 No

2290

(94.9%)

588

(98.2%)

81

(97.6%)

1083

(96.4%)

1126

(93.4%)

27

(100%)

274

(99.3%)

287

(97.0%)

 

 Yes

122

(5.1%)

11

(1.8%)

2

(2.4%)

40

(3.6%)

80

(6.6%)

-

2

(0.7%)

9

(3.0%)

 

FTR

        

PPD < 0.05

PDP = 0.21

 

122

(18.0%)

11

(7.9%)

2

(14.3%)

40

(13.6%)

80

(21.6%)

-

2

(3.3%)

9

(11.8%)

 
  1. Overall outcomes according to PD and DP and according to age group. Continuous data are shown as median, categorial data are shown as absolute (relative). Kruskal- Wallis test, Pearson’s chi square test and Fisher’s exact test used, comparing PD and DP resection within Early-, Middle- and Late-Onset group. Post hoc testing was calculated with Jonckheere-Terpstra test
  2. ICU intensive care unit, POPF postoperative pancreatic fistula, PPH postpancreatectomy hemorrhage, DGE delayed gastric emptying
Back to article page

BMC Surgery

ISSN: 1471-2482

Contact us