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Table 4 Risk factors for FTR in PD and DP

From: Perioperative outcomes in an age-adapted analysis of the German StuDoQ|Pancreas registry for PDAC

Univariable logistic regression

Pancreaticoduodenectomy

Distal pancreatectomy

Variable

Category/ Units

 

OR

[95% CI]

P-Value

OR

[95% CI]

P-Value

Age

Years/10

 

1.48

[1.17—1.87]

0.001

2.89

[1.16—7.25]

0.023

BMI

kg/m2

 

1.02

[0.99—1.04]

0.164

1.08

[0.93—1.25]

0.323

DGAV certification

No*

Yes

0.76

[0.51—1.13]

0.173

1.24

[0.31—4.93]

0.757

ASA

1/2*

3/4/5

2.30

[1.47—3.58]

0.001

1.15

[0.33—3.94]

0.829

Pancreatic duct

 < 3mm*

 > 3mm

1.02

[0.65—1.62]

0.929

0.42

[0.07—2.46]

0.336

Pancreatic texture

soft*

hard

0.74

[0.45—1.13]

0.151

0.48

[0.06—4.20]

0.510

Bilirubin

mg/dl

 

1.02

[0.98—1.05]

0.086

0.19

[0.01—2.84]

0.227

CA19-9

(U/ml)/100

 

1.01

[1.01—1.02]

0.023

0.98

[0.89—1.07]

0.639

CEA

n/ml

 

0.98

[0.98—1.01]

0.685

1.03

[0.99—1.06]

0.112

Diabetes mellitus

No*

Yes,

no insulin

1.67

[0.98—2.84]

0.059

0.62

[0.07—5.26]

0.659

  

Yes,

insulin dependent

1.18

[0.70—1.199]

0.545

3.39

[0.77—14.90]

0.106

Multivariable logistic regression

Pancreaticoduodenectomy

Variable

Category/ Units

 

OR

[95% CI]

P-Value

Age

Years/10

 

1.40

[1.07—1.83]

0.014

ASA

1/2*

3/4/5

2.11

[1.27—3.53]

0.004

CA19-9

U/ml

 

1.00

[1.00—1.00]

0.044

  1. Predictors of FTR. Results were derived from univariable and multivariable logistic regression including all patients in PD respectively DP group with Clavien–Dindo grade ≥ 3a. Only predictors with p < 0,05 were included in the multivariable analysis
  2. CI confidence interval, OR odds ratio
  3. Asterix (*) indicates reference group