Table 2 Patient’s intra-operative results in training cohort and validation cohort
From: Risk assessment of hyperbilirubinemia using a three-factor model after cardiac surgery
Parameters | Training cohort | P | Validation cohort | P | P (T: V) | |||
|---|---|---|---|---|---|---|---|---|
All (n = 411) | Non-HB (n = 212) | HB (n = 79) | Non-HB (n = 83) | HB (n = 37) | ||||
Intra-operative results | ||||||||
Surgery time, minute | 367.04 ± 120.00 | 350.05 ± 108.30 | 414.65 ± 144.84 | < 0.001 | 341.70 ± 93.32 | 419.65 ± 143.39 | < 0.001 | 0.887 |
CPBT, minute | 169.66 ± 85.90 | 160.24 ± 80.39 | 199.53 ± 91.46 | < 0.001 | 148.33 ± 67.35 | 207.70 ± 112.66 | < 0.001 | 0.647 |
Aortic occlusion time, minute | 93.82 ± 49.79 | 87.69 ± 44.49 | 116.66 ± 58.65 | < 0.001 | 82.12 ± 40.00 | 106.38 ± 60.73 | < 0.001 | 0.271 |
Minimum temperature, ℃ | 34.29 ± 1.95 | 34.33 ± 2.28 | 33.93 ± 1.98 | 0.172 | 34.60 ± 0.68 | 34.10 ± 1.63 | 0.018 | 0.287 |
Sevoflurane inhalation, (%) | 385 (93.7) | 195 (92.0) | 76 (96.2) | 0.206 | 77 (92.8) | 37 (100.0) | 0.093 | 0.478 |
Dexmedetomidine, (%) | 266 (64.7) | 145 (68.4) | 47 (59.5) | 0.154 | 53 (63.9) | 21 (56.8) | 0.460 | 0.405 |
Dopamine, (%) | 56 (13.6) | 24 (11.3) | 12 (15.2) | 0.373 | 15 (18.1) | 5 (13.5) | 0.536 | 0.248 |
Dobutamine, (%) | 239 (58.2) | 123 (58.0) | 49 (62.0) | 0.536 | 73 (88.0) | 34 (91.9) | 0.521 | 0.541 |
Norepinephrine, (%) | 350 (85.2) | 172 (81.1) | 71 (89.9) | 0.074 | 71 (85.5) | 75 (90.4) | 0.340 | 0.142 |
Adrenaline, (%) | 66 (16.1) | 33 (15.6) | 13 (16.5) | 0.853 | 12 (14.5) | 8 (21.6) | 0.331 | 0.829 |
Heart valve surgeries, (%) | 237 (57.7) | 118 (55.7) | 47 (59.5) | 0.405 | 47 (56.6) | 25 (67.6) | 0.259 | 0.538 |
CABG, (%) | 57 (13.9) | 39 (18.4) | 2 (2.5) | 0.001 | 13 (15.7) | 3 (8.1) | 0.261 | 0.840 |
VR + CABG, (%) | 16 (3.9) | 7 (3.3) | 3 (3.8) | 0.836 | 4 (4.8) | 2 (5.4) | 0.892 | 0.456 |
Vascular surgery, (%) | 40 (9.7) | 14 (6.6) | 17 (21.5) | < 0.001 | 4 (4.8) | 5 (13.5) | 0.095 | 0.327 |
Congenital surgery, (%) | 51 (12.4) | 28 (13.2) | 10 (12.7) | 0.902 | 12 (14.5) | 1 (2.7) | 0.056 | 0.534 |
Other cardiac surgeries (%) | 10 (2.4) | 6 (2.8) | 0 (0.0) | 0.131 | 3 (3.6) | 1 (2.7) | 0.797 | 0.447 |
Fluid intake and output | ||||||||
Blood loss, ml | 566.67 ± 329.37 | 535.61 ± 301.60 | 702.53 ± 451.34 | < 0.001 | 480.12 ± 185.60 | 648.65 ± 334.89 | < 0.001 | 0.172 |
RBC, ml | 375.47 ± 365.64 | 327.36 ± 328.53 | 525.13 ± 420.73 | < 0.001 | 277.53 ± 330.27 | 551.35 ± 375.90 | < 0.001 | 0.631 |
Plasma, ml | 445.50 ± 430.60 | 388.68 ± 210.59 | 522.78 ± 302.00 | < 0.001 | 525.30 ± 330.27 | 427.03 ± 245.68 | 0.479 | 0.135 |
Cryoprecipitate, U | 0.73 ± 2.59 | 0.44 ± 2.12 | 1.04 ± 3.02 | 0.061 | 0.94 ± 2.90 | 1.22 ± 3.17 | 0.641 | 0.135 |
PLT, U | 0.36 ± 0.56 | 0.32 ± 0.51 | 0.42 ± 0.63 | 0.195 | 0.30 ± 0.56 | 0.54 ± 0.65 | 0.041 | 0.679 |