Table 4 Multivariate regression analyses on anastomotic leakage-related factors

Neoadjuvant therapy

11.994

2.981–48.256

 < 0.01

Tumor location

5.306

1.383–20.358

0.015

Anastomosis bleeding

58.822

15.294–226.233

 < 0.01

Number of staple firings used (≥ 3)

24.752

6.212–98.619

 < 0.01

Defunctioning stoma

0.051

0.012–0.221

 < 0.01

Reinforcing sutures

0.054

0.009–0.315

0.001