Table 4 Comparative studies on incidence of PEI after pancreatic resection
From: Pancreatic exocrine insufficiency after pancreatic resection: a systematic review
Study | Prospective or retrospective | Sample size | Surgical procedures | Indication for surgical procedure | Test used | Reported PEI incidence | Reported Sensitivity -Specificity | Significant differences |
|---|---|---|---|---|---|---|---|---|
Benini 2019 [23] | Retrospective | 34 | PD 100% DP 0% | Malignant lesions, NET, benign lesions, other | FE-1 test Faecal fat | 84% 77% | NA | NA |
Halloran 2011 [25] | Prospective | 40 | PD 93% DP 7% | Malignant lesions | FE-1 test Faecal fat | 83% 55% | Sens. 91% Specif. 35% Accuracy 70% for FE-1 (CFA > 93% as reference standard) | NA |
Lemaire 2000 [32] | Prospective | 19 | PD 89% DP 0% | Malignant lesion (pancreatic cancer excluded), benign lesions | FE-1 test Faecal fat | 100% 94% | Sens. 91% Specif. 35% for FE-1 (FFE > 6 g as reference standard) | NA |
Muniz 2014 [35] | Retrospective | 15 | PD 100% DP 0% | NA | FE-1 test 13 C breath test | 47% 47% | NA | NA |
Nakamura 2009 [36] | Retrospective | 95 | PD 54% DP 14% | Malignant lesions, NET, benign lesions, other | FE-1 test 13 C breath test | 62% 88% | Sens. 90% Specif. 52% Accuracy 62% for FE-1 Sens. 69% Specif. 93% Accuracy 88% for 13 C breath test (steatorrhea as reference standard) | NA |
Powell-Brett 2024 [42] | Prospective | 26 | PD 100% DP 0% | Malignant lesions, NET, benign lesions | FE-1 test 13 C breath test | 88% 60% | NA | NA |