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Table 5 Analysis of postoperative brain-sparing effect indicators in patients (`x±s)

From: Effects of sufentanil on immune response, pain mediators and brain-sparing effect in patients with breast cancer undergoing radical mastectomy

Groups

n

MMSE (score)

Da-jvO2(ml/L)

  

Before surgery

24 hours after surgery

48 hours after surgery

Before surgery

24 hours after surgery

48 hours after surgery

The sufentanil group

59

29.32±1.31

24.38±2.47***

27.85±2.77#

41.18±7.14

63.63±7.37***

54.25±5.11##

The control group

59

29.36±1.48

21.28±3.03***

25.03±2.16###

42.41±5.05

67.76±6.85***

68.76±6.18###

FTreatment value/PTreatment value

  

4.196/0.041

  

5.513/0.013

 

FTime value/PTime value

  

4.738/0.038

  

4.973/0.034

 

FTreatment×Time value/PTreatment×Time value

  

3.976/0.046

  

9.254/0.001

 

Groups

n

S-jvO2(%)

CEO2(%)

  

Before surgery

24 hours after surgery

48 hours after surgery

Before surgery

24 hours after surgery

48 hours after surgery

The sufentanil group

59

72.83±5.25

61.24±4.17***

66.16±4.24##

20.74±3.69

26.91±2.84***

21.28±3.18#

The control group

59

73.53±5.38

65.65±4.23***

68.14±3.17##

21.07±3.69

29.47±4.35***

25.25±3.03###

FTreatment value/PTreatment value

  

4.689/0.030

  

9.778/0.001

 

FTime value/PTime value

  

6.836/0.027

  

10.326/0.001

 

FTreatment×Time value/PTreatment×Time value

  

10.201/0.001

  

12.785/0.001

 
  1. Note: ***P<0.001 compared with preoperative data; #P<0.05, ##P<0.0 and ###P<0.001 compared with postoperative 24 hours.