From: Predictors of postoperative recurrence of pheochromocytoma: a monocentric study
Variables | Overall | No-recurrence (n = 416) | Recurrence (n = 35) | t/u/x2 | P Value | |
---|---|---|---|---|---|---|
Daily preoperative phenoxybenzamine dose (ml) | 20.0(15.0,35.0) | 20.0(12.5,35.0) | 17.5(10.6,25.0) | -0.825 | 0.409 | |
Duration of phenazopyridine administration (day) | 26.0 ± 15.7 | 27.6 ± 16.4 | 21.2 ± 12.8 | 2.021 | 0.044* | |
Dos*time/weight | 7.1(4.1,13.3) | 7.5(4.4,13.1) | 5.7(3.9,9.5) | -1.364 | 0.173 | |
SBP at admission | 130.0(120.0,142.5) | 130.0(120.0,150.0) | 127.0(120.0,140.0) | -0.714 | 0.475 | |
DBP at admission | 80.0(70.0,90.0) | 80.0(70.0,90.0) | 85.0(70.0,90.0) | -2.217 | 0.027* | |
Operation mode | 7.267 | 0.026* | ||||
Open | 32(7.10%) | 25(6.00%) | 7(20.00%) | |||
Laparoscopic | 319(70.70%) | 299(71.90%) | 20(57.10%) | |||
Robotic | 100(22.20%) | 92(22.10%) | 8(22.90%) | |||
Surgical approach | 1.467 | 0.226 | ||||
open | 32(7.10%) | 25(6.00%) | 7(20.00%) | |||
Transperitoneal | 109(26.00%) | 99(25.30%) | 10(35.70%) | |||
Retroperitoneal | 310(74.00%) | 292(74.70%) | 18(64.30%) | |||
Postoperative SBP (mmHg) | 120.0(110.0,130.0) | 120.0(106.3,137.5) | 120.0(110.0,135.0) | -0.406 | 0.684 | |
Postoperative DBP (mmHg) | 70.0(60.0,80.0) | 70.0(60.0,80.0) | 70.0(60.3,87.5) | -0.616 | 0.538 | |
HR max | 106.67 ± 17.40 | 106.43 ± 16.54 | 107.57 ± 20.58 | -0.345 | 0.734 | |
HR min | 59.58 ± 10.40 | 58.09 ± 8.74 | 65.22 ± 13.88 | -3.718 | < 0.001* | |
HR range | 47.08 ± 16.59 | 48.34 ± 16.35 | 42.35 ± 16.89 | 1.896 | 0.051 | |
the number of episodes of intraoperative HR over 120 bpm | 5.566 | 0.018* | ||||
< 6 | 434(96.23%) | 404 (97.12%) | 30 (85.72%) | |||
≥ 6 | 17(3.77%) | 12 (2.88%) | 5 (14.28%) | |||
One-time HR range | 24.06 ± 12.34 | 23.85 ± 12.57 | 24.85 ± 11.58 | -0.351 | 0.674 | |
SBP max | 163.01 ± 24.43 | 163.00 ± 24.48 | 163.09 ± 24.38 | -0.020 | 0.984 | |
SBP min | 95.54 ± 13.94 | 95.50 ± 13.49 | 95.96 ± 17.77 | -0.171 | 0.856 | |
SBP range | 66.88 ± 27.73 | 66.85 ± 27.23 | 67.13 ± 32.45 | -0.061 | 0.955 | |
One-time SBP range | 45.73 ± 24.71 | 46.04 ± 23.77 | 42.94 ± 32.25 | 0.719 | 0.489 | |
DBP max | 90.10 ± 13.10 | 89.97 ± 13.23 | 91.25 ± 12.06 | -0.543 | 0.589 | |
DBP min | 53.77 ± 8.62 | 53.68 ± 8.35 | 54.63 ± 10.84 | -0.617 | 0.540 | |
DBP range | 35.49 ± 14.47 | 35.37 ± 14.37 | 36.62 ± 15.56 | -0.476 | 0.633 | |
One-time DBP range | 22.88 ± 11.46 | 23.02 ± 11.41 | 21.62 ± 12.04 | 0.674 | 0.498 | |
MAP max | 110.44 ± 22.55 | 110.03 ± 23.26 | 114.22 ± 14.19 | -1.027 | 0.305 | |
MAP min | 66.95 ± 14.02 | 66.62 ± 14.13 | 70.04 ± 12.69 | -1.353 | 0.177 | |
MAP range | 43.49 ± 17.89 | 43.41 ± 17.66 | 44.18 ± 20.22 | -0.234 | 0.815 | |
the number of episodes of intraoperative hemodynamic instability | 8.648 | 0.003* | ||||
< 8 | 442(98.00%) | 411 (98.56%) | 31 (88.57%) | |||
≥ 8 | 9(2.00%) | 5 (1.44%) | 4 (11.43%) | |||
Duration of intraoperative hemodynamic instability | 16.94 ± 25.46 | 16.30 ± 22.99 | 22.59 ± 41.65 | -1.364 | 0.173 | |
Intraoperative bleeding (ml) | 100.0(50.0,312.5) | 100.0(50.0,275.0) | 175.0(100.0,450.0) | -2.105 | 0.035* |