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Table 3 Univariate and multivariate analyses

From: Predictors of postoperative recurrence of pheochromocytoma: a monocentric study

Variables

Univariate analyses

Multivariate analyses

 

HR(95% CI)

P value

HR(95% CI)

P value

Age

0.95 (0.92, 0.97)

< 0.001*

0.95 (0.91, 0.99)

0.001*

Sex(female)

0.79 (0.39, 1.64)

0.532

  

BMI

0.96 (0.88, 1.04)

0.310

  

Drug dosage per day

0.99 (0.96, 1.02)

0.626

  

Length of medication

0.96(0.92–0.99)

0.012*

1.01(0.91,1.12)

0.788

Hypertension

2.36 (1.18, 5.74)

0.018*

7.14 (1.23,41.54)

0.029*

Diabetes

0.71 (0.29, 1.73)

0.448

  

History of PCC recurrence

10.20 (4.35, 23.91)

< 0.001*

69.35(7.97,603.73)

< 0.001*

Family history of hypertension

1.77(0.87,3.64)

0.118

16.30(1.55,251.8)

< 0.001*

Bilateral tumor

5.25 (2.23, 12.37)

0.001*

7.38(1.04,52.24)

0.045*

Left or right side

0.79 (0.35, 1.79)

0.568

  

Ki-67 ≥ 5

1.07(1.00,1.14)

0.045*

26.70(0.13,5519.68)

0.227

SBP at admission

0.88(0.79,1.01)

0.339

  

DBP at admission

1.03 (1.01, 1.06)

0.014*

  

Surgery approach (open or not)

0.31 (0.13, 0.76)

0.011*

1.00(0.07,12.64)

0.999

Surgery approach (laparoscopic/robotic)

1.36 (0.53, 3.48)

0.519

  

Surgery trans (transperitoneal/retroperitoneal)

0.56 (0.24, 1.33)

0.191

  

Tumor size

1.06(0.92,1.21)

0.436

1.65(1.04,2.60)

0.031*

The number of episodes of intraoperative HR over 120 ≥ 6 bpm

4.32(1.28,14.65)

0.019*

121.43(0.03,584419.65)

0.267

the number of episodes of intraoperative hemodynamic instability ≥ 8

5.69(1.72,18.88)

0.005*

114.91(1.68,7870.89)

0.034*

duration of intraoperative hemodynamic instability

1.01(1.00,1.02)

0.121

1.12(1.02,1.25)

0.025*

HR range

0.99(0.97,1.01)

0.376

  

One-time HR range

1.02(0.99,1.05)

0.134

  

SBP range

1.00(0.99,1.02)

0.201

  

One-time SBP range

1.00(0.99,1.01)

0.181

  

DBP range

1.01(0.99,1.04)

0.294

  

One-time DBP range

1.00(0.97,1.03)

0.969

  

MAP range

1.01(0.99,1.03)

0.469

  
  1. BMI: Body Mass Index; NE: Norepinephrine; E: Epinephrine; DA: Dopamine. SBP: Systolic Blood Pressure; DBP: Diastolic Blood Pressure; HR: Heart Rate; BPM: Beats Per Minute; MAP: Mean Arterial Pressure
  2. * Significant difference