From: Predictors of postoperative recurrence of pheochromocytoma: a monocentric study
Variables | Univariate analyses | Multivariate analyses | ||||
---|---|---|---|---|---|---|
HR(95% CI) | P value | HR(95% CI) | P value | |||
Age | 0.95 (0.92, 0.97) | < 0.001* | 0.95 (0.91, 0.99) | 0.001* | ||
Sex(female) | 0.79 (0.39, 1.64) | 0.532 | ||||
BMI | 0.96 (0.88, 1.04) | 0.310 | ||||
Drug dosage per day | 0.99 (0.96, 1.02) | 0.626 | ||||
Length of medication | 0.96(0.92–0.99) | 0.012* | 1.01(0.91,1.12) | 0.788 | ||
Hypertension | 2.36 (1.18, 5.74) | 0.018* | 7.14 (1.23,41.54) | 0.029* | ||
Diabetes | 0.71 (0.29, 1.73) | 0.448 | ||||
History of PCC recurrence | 10.20 (4.35, 23.91) | < 0.001* | 69.35(7.97,603.73) | < 0.001* | ||
Family history of hypertension | 1.77(0.87,3.64) | 0.118 | 16.30(1.55,251.8) | < 0.001* | ||
Bilateral tumor | 5.25 (2.23, 12.37) | 0.001* | 7.38(1.04,52.24) | 0.045* | ||
Left or right side | 0.79 (0.35, 1.79) | 0.568 | ||||
Ki-67 ≥ 5 | 1.07(1.00,1.14) | 0.045* | 26.70(0.13,5519.68) | 0.227 | ||
SBP at admission | 0.88(0.79,1.01) | 0.339 | ||||
DBP at admission | 1.03 (1.01, 1.06) | 0.014* | ||||
Surgery approach (open or not) | 0.31 (0.13, 0.76) | 0.011* | 1.00(0.07,12.64) | 0.999 | ||
Surgery approach (laparoscopic/robotic) | 1.36 (0.53, 3.48) | 0.519 | ||||
Surgery trans (transperitoneal/retroperitoneal) | 0.56 (0.24, 1.33) | 0.191 | ||||
Tumor size | 1.06(0.92,1.21) | 0.436 | 1.65(1.04,2.60) | 0.031* | ||
The number of episodes of intraoperative HR over 120 ≥ 6 bpm | 4.32(1.28,14.65) | 0.019* | 121.43(0.03,584419.65) | 0.267 | ||
the number of episodes of intraoperative hemodynamic instability ≥ 8 | 5.69(1.72,18.88) | 0.005* | 114.91(1.68,7870.89) | 0.034* | ||
duration of intraoperative hemodynamic instability | 1.01(1.00,1.02) | 0.121 | 1.12(1.02,1.25) | 0.025* | ||
HR range | 0.99(0.97,1.01) | 0.376 | ||||
One-time HR range | 1.02(0.99,1.05) | 0.134 | ||||
SBP range | 1.00(0.99,1.02) | 0.201 | ||||
One-time SBP range | 1.00(0.99,1.01) | 0.181 | ||||
DBP range | 1.01(0.99,1.04) | 0.294 | ||||
One-time DBP range | 1.00(0.97,1.03) | 0.969 | ||||
MAP range | 1.01(0.99,1.03) | 0.469 |