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Table 5 Impact of DP on blood glucose homeostasis in diabetic patients (n = 30)

From: Glucose metabolism after distal pancreatectomy - deterioration of beta cell function becomes noticeable at an early stage: a retrospective cohort study

Variable

Before surgery

3 Months

12 Months

p-Value

BMI kg/m2 (IQR)

27 (25.1–30.4)

26 (23.3–29)

24.3 (21.4–28)

< 0.001*

Fasting glucose mmol/L (IQR)

8.21 (7–11)

7.3 (5.93–8.17)

7.9 (5.8–12.41)

0.11*

HbA1c % (IQR)

7.4 (6.6–8.4)

6.2 (5.8–7.7)

6.8 (6.1–7.9)

0.26*

Insulin nmol/L (IQR)

0.07 (0.04–0.11)

0.07 (0.03–0.11)

0.07 (0.03–0.1)

0.34*

Proinsulin nmol/L (IQR)

4.65 (2.2–7)

3.9 (2.2–6.1)

2.8 (1.9–5.8)

0.22#

C-Peptide nmol/L (IQR)

0.89 (0.68–1.32)

0.66 (0.44–1.08)

0.74 (0.5–1.01)

0.27*

HOMA2-%B (IQR)

63.1 (41.8–91.1)

61.1 (40.9–86.6)

70.3 (35.9–95.8)

1*

HOMA2-%S (IQR)

50.2 (34.9–79.6)

46.5 (35.5–91.7)

48.4 (41.9–69.9)

1*

HOMA2-IR (IQR)

2 (1.25–2.86)

2.15 (1.09–2.82)

2.7 (1.44–2.39)

0.4#

  1. # - the p-values in Table 5 refer to the comparison between preoperative and postoperative values after 3 months, * - the p-values reflect the comparison between preoperative and postoperative values after 12 months
  2. Abbreviations: HOMA2, updated Homeostasis Model Assessment; IQR - interquartile range