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Table 4 Subgroup analysis by peripheral artery disease status

From: Comparison and evaluation of negative pressure wound therapy versus standard wound care in the treatment of diabetic foot ulcers

Subgroup

NPWT Complete Closure (%)

SWC Complete Closure (%)

Risk Ratio (95% CI)

P value

PAD-positive (n = 33)

48.0

20.0

2.40 (1.12–5.15)

0.042

PAD-negative (n = 58)

55.2

30.4

1.82 (1.05–3.15)

0.031

  1. Note: Risk ratios (RR) and 95% confidence intervals (CI) were calculated using Mantel-Haenszel methods; Interaction term (treatment × PAD status) in logistic regression: P = 0.28, indicating no significant effect modification by PAD status