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Table 5 Subgroup analysis by arterial disease severity and revascularization status

From: Comparison and evaluation of negative pressure wound therapy versus standard wound care in the treatment of diabetic foot ulcers

Subgroup

NPWT Complete Closure (%)

SWC Complete Closure (%)

Risk Ratio (95% CI)

P-value

ABI Category

    

Severe ischemia (ABI < 0.4)

36.4

12.5

2.91 (1.08–7.85)

0.038

Moderate ischemia (ABI 0.4–0.7)

48.6

22.2

2.19 (1.14–4.20)

0.019

Normal/mild ischemia (ABI > 0.7)

55.2

30.4

1.82 (1.05–3.15)

0.031

Revascularization Status

    

Revascularized (n = 16)

50.0

18.8

2.67 (0.98–7.25)

0.054

Non-revascularized (n = 75)

52.1

28.6

1.82 (1.10–3.02)

0.021

  1. Note: Interaction term (ABI category × treatment): P = 0.23; Revascularization × treatment: P = 0.15