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Table 1 Patient clinical characteristics(n = 890)

From: The prognostic value of the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in colorectal cancer and colorectal anastomotic leakage patients: a retrospective study

Variables

All patients (n = 890)

AL patients (n = 102)

Non-AL patients(n = 788)

t/ Z/ χ2

P

Age(years)

68.66 ± 12.66

68.88 ± 12.86

68.63 ± 12.64

0.843

0.198

BMI(kg/m2)

23.05 ± 3.18

23.03 ± 3.81

23.04 ± 3.18

0.978

0.028

Hospitalization (day)

22.51 ± 11.71

37.22 ± 16.21

20.60 ± 9.46

10.355

< 0.001

Gender

 Male

532(59.8)

74(72.55)

458(58.12)

7.818

0.005

 Female

358(40.2)

28(27.45)

330(41.88)

Smoking

 Yes

125(14.0)

28(27.45)

97(12.31)

18.062

< 0.001

 No

765(86.0)

74(72.55)

691(87.70)

Alcohol

 Yes

84(9.4)

14(13.73)

70(8.88)

2.477

0.115

 No

806(90.6)

88(86.27)

718(91.12)

Diabetes

 Yes

70(7.9)

16(15.69)

54(6.85)

9.725

0.002

 No

820(92.1)

86(84.31)

734(93.15)

Hypertension

 Yes

202(22.7)

33(32.35)

169(21.45)

6.122

0.013

 No

688(77.3)

69(67.65)

619(78.55)

Cardiovascular disease

 Yes

62(7.0)

11(10.78)

51(6.47)

2.591

0.107

 No

828(93.0)

91(89.22)

737(93.53)

Abdominal operation

 Yes

171(19.2)

41(40.20)

130(16.50)

32.677

< 0.001

 No

719(80.8)

61(59.80)

658(83.50)

Intestinal polyps

 Yes

151(17.0)

56(54.90)

95(12.06)

117.684

< 0.001

 No

739(83.0)

46(45.10)

693(87.94)

Chemotherapy

 Yes

480(53.9)

49(48.04)

431(54.70)

1.610

0.204

 No

410(46.1)

53(51.96)

357(45.30)

Surgical options

 laparoscopy

667(74.9)

52(50.98)

615(78.05)

35.230

< 0.001

 open

223(25.1)

50(49.02)

173(21.95)

Drainage tube

 Yes

625(70.22)

101(99.02)

90(88.24)

17.872

< 0.001

 No

265(29.78)

1(0.98)

12(11.76)

Tumor location

 descending colon

124(13.9)

15(14.71)

109(13.83)

3.750

0.153

 sigmoid colon

274(30.8)

23(22.55)

251(31.85)

 rectum

492(55.3)

64(62.75)

428(54.31)

Tumor diameter

 < 5 cm

503(56.5)

55(53.92)

448(56.85)

0.316

0.574

 ≥ 5 cm

387(43.5)

47(46.08)

340(43.15)

Tumor differentiation grade

 Poor

6(0.7)

2(1.96)

4(0.51)

3.973

0.137

 Medium

849(95.4)

98(96.08)

751(95.30)

 High

35(4.3)

2(1.96)

33(4.19)

TNM Stage

 I

241(27.1)

20(19.61)

221(28.05)

10.531

0.015

 II

340(38.2)

53(51.96)

288(36.55)

 III

217(24.4)

24(23.53)

201(25.51)

 IV

83(9.3)

5(4.90)

78(9.90)

CEA(ng/mL)

 ≥ 5

402(45.17)

47(46.08)

355(45.05)

0.039

0.844

 < 5

488(54.83)

55(53.92)

433(54.95)

 Leukocyte (109/L)

6.25 ± 2.68

6.32 ± 2.53

6.24 ± 2.71

0.742

0.330

 Neutrophil (109/L)

4.10 ± 3.32

4.51 ± 3.52

3.95 ± 2.11

1.227

0.223

 Platelet (109/L)

221.98 ± 83.31

236.75 ± 87.97

220.06 ± 82.55

1.776

0.079

 Lymphocyte (109/L)

1.62 ± 0.67

1.48 ± 0.60

1.63 ± 0.68

-2.454

0.016

 Hemoglobin (g/L)

117.44 ± 21.91

118.12 ± 22.92

117.35 ± 21.79

0.338

0.736

 Albumin (g/dL)

38.61 ± 4.95

38.12 ± 4.02

38.68 ± 5.05

-1.402

0.164

 NAR(109/L)

0.11 ± 0.06

0.12 ± 0.09

0.10 ± 0.06

2.117

0.037

 NLR(109/L)

3.05 ± 2.88

3.65 ± 3.19

2.98 ± 2.83

2.116

0.037

 PLR(109/L)

0.11 ± 0.06

0.11 ± 0.06

0.10 ± 0.06

16.651

< 0.001