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Table 2 Logistic regression analysis of CAL patients (n = 102)

From: The prognostic value of the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in colorectal cancer and colorectal anastomotic leakage patients: a retrospective study

Variable

 

Univariate analysis

Multivariate analysis

 

OR(95%CI)

P

OR(95%CI)

P

Age(years)

(≥ 60/ < 60)

1.002 (0.985–1.018)

0.847

  

BMI(kg/m2)

 

1.015 (0.952–1.082)

0.654

  

Hospitalization (day)

(≥ 25.5/ < 25.5)

1.093 (1.074–1.112)

< 0.001

1.095 (1.072–1.118)

< 0.001

Gender

(Male/Female)

1.904 (1.205–3.008)

0.006

1.750 (0.987–3.101)

0.055

Smoking

(Yes/No)

2.770 (1.705–4.502)

< 0.001

1.307 (0.730–2.340)

0.368

Alcohol

(Yes/No)

1.632 (0.882–3.018)

0.119

  

Diabetes

(Yes/No)

2.529 (1.387–4.612)

0.002

1.248 (0.615–2.533)

0.539

Hypertension

(Yes/No)

1.752 (1.119–2.743)

0.014

0.818 (0.488–1.373)

0.448

Cardiovascular disease

(Yes/No)

1.747 (0.879–3.472)

0.112

  

Abdominal operation

(Yes/No)

3.402 (2.195–5.273)

< 0.001

2.162 (1.303–3.588)

0.003

Intestinal polyps

(Yes/No)

8.881 (5.690–13.859)

< 0.001

4.504 (2.777–7.306)

< 0.001

Chemotherapy

(Yes/No)

0.766 (0.507–8.857)

0.205

  

Surgical options

(Yes/No)

0.293 (0.192–0.447)

< 0.001

0.313 (0.163–0.600)

< 0.001

Drainage tube

(Yes/No)

7.763 (6.626–10.314)

< 0.001

5.636 (3.441–9.970)

0.002

Tumor location

(Descending/ Sigmoid/ Rectum)

1.162 (0.864–1.563)

0.321

  

Tumor diameter

(≥ 5/ < 5)

0.888 (0.587–1.344)

0.574

  

Tumor differentiation

(Poor/ Medium/ High)

0.363 (0.110–1.198)

0.096

  

TNM Stage

(I/II/III/IV)

0.960 (0.768–1.199)

0.719

  

CEA(ng/mL)

 

1.000 (0.994–1.006)

0.944

  

Leukocyte (109/L)

 

1.011 (0.939–1.088)

0.771

  

Neutrophil (109/L)

 

1.086 (1.010–1.168)

0.027

1.329 (0.855–2.064)

0.206

Platelet (109/L)

 

1.002 (1.000–1.004)

0.080

1.008 (1.001–1.014)

0.022

Lymphocyte (109/L)

 

0.687 (0.486–0.969)

0.033

0.605 (0.336–1.090)

0.095

Hemoglobin (g/L)

 

1.016 (1.003–1.029)

0.015

1.003 (0.991–1.015)

0.617

Albumin (g/dL)

 

0.914 (0.818–1.022)

0.114

  

NLR(109/L)

 

1.790 (1.206–2.129)

0.031

0.171 (0.218–0.562)

0.022

PLR(109/L)

 

1.803 (1.401–2.805)

0.001

1.605 (1.001–2.009)

0.022