Table 6 Clinical characterization of OS and DFS in CAL patients
Variables | OS (n = 46) | DFS (n = 16) | t/ Z/ χ2 | P |
|---|---|---|---|---|
Age(years) | 76.54 ± 9.35 | 59.81 ± 14.86 | 12.133 | < 0.001 |
BMI(kg/m2) | 23.31 ± 3.73 | 23.24 ± 2.73 | 0.133 | 0.895 |
Hospitalization (day) | 39.83 ± 15.31 | 32.88 ± 13.54 | 3.076 | 0.004 |
Gender | ||||
 Male | 35(76.09) | 11(68.75) | 0.334 | 0.563 |
 Female | 11(23.91) | 5(31.25) | ||
Smoking | ||||
 Yes | 34(73.91) | 4(25.00) | 11.971 | < 0.001 |
 No | 12(26.09) | 12(75.00) | ||
Alcohol | ||||
 Yes | 42(91.30) | 2(12.5) | 35.780 | < 0.001 |
 No | 4(8.70) | 14(87.50) | ||
Diabetes | ||||
 Yes | 39(84.78) | 1(6.25) | 31.981 | < 0.001 |
 No | 7(15.22) | 15(93.75) | ||
Hypertension | ||||
 Yes | 15(32.61) | 2(12.5) | 2.412 | 0.013 |
 No | 31(67.39) | 14(87.50) | ||
Cardiovascular disease | ||||
 Yes | 7(15.22) | 1(6.25) | 2.591 | 0.120 |
 No | 39(84.78) | 15(93.75) | ||
Abdominal operation | ||||
 Yes | 31(67.39) | 3(18.75) | 11.341 | < 0.001 |
 No | 15(32.61) | 13(81.25) | ||
Intestinal polyps | ||||
 Yes | 29(63.04) | 3(18.75) | 23.525 | < 0.001 |
 No | 17(36.96) | 13(81.25) | ||
Chemotherapy | ||||
 Yes | 22(47.83) | 11(68.75) | 2.088 | 0.149 |
 No | 24(52.17) | 5(31.25) | ||
Surgical options | ||||
 laparoscopy | 39(92.86) | 14(87.50) | 0.071 | 0.790 |
 open | 7(15.22) | 2(12.5) | ||
Drainage tube | ||||
 Yes | 45(97.83) | 15(93.75) | 0.632 | 0.427 |
 No | 1(2.17) | 1(6.25) | ||
Tumor location | ||||
 descending colon | 5(10.87) | 1(6.25) | 0.570 | 0.752 |
 sigmoid colon | 11(23.91) | 3(18.75) | ||
 rectum | 30(65.22) | 12(75.00) | ||
Tumor diameter | ||||
 < 5 cm | 21(45.65) | 14(87.50) | 8.456 | 0.004 |
 ≥ 5 cm | 25(54.35) | 2(12.5) | ||
Tumor differentiation grade | ||||
 Poor | 5(10.87) | 1(6.25) | 1.307 | 0.520 |
 Medium | 44(95.65) | 14(87.50) | ||
 High | 1(2.17) | 1(6.25) | ||
TNM Stage | ||||
 I | 5(10.87) | 6(37.5) | 7.934 | 0.047 |
 II | 12(26.09) | 5(31.25) | ||
 III | 24(52.17) | 3(18.75) | ||
 IV | 5(10.87) | 2(12.5) | ||
CEA(ng/mL) | ||||
 ≥ 5 | 28(17.39) | 11(68.75) | 0.316 | 0.574 |
 < 5 | 18(39.13) | 5(31.25) | ||
 Leukocyte (109/L) | 5.97 ± 1.65 | 6.44 ± 2.95 | -1.948 | 0.058 |
 Neutrophil (109/L) | 4.47 ± 4.17 | 5.15 ± 4.32 | -1.107 | 0.274 |
 Platelet (109/L) | 219.43 ± 71.43 | 239.50 ± 126.28 | -1.905 | 0.063 |
 Lymphocyte (I109/L) | 1.53 ± 0.59 | 1.53 ± 0.65 | 0.013 | 0.990 |
 Hemoglobin (g/L) | 116.46 ± 23.11 | 125.38 ± 21.96 | -2.619 | 0.012 |
 Albumin (g/dL) | 37.92 ± 4.08 | 38.48 ± 3.81 | -0.923 | 0.361 |
 NLR(109/L) | 3.40 ± 3.11 | 3.86 ± 1.22 | -1.014 | 0.316 |
 PLR(109/L) | 169.37 ± 110.08 | 162.61 ± 66.50 | 0.417 | 0.679 |